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Trinity College Dublin

Ongoing Research Projects supported by TCHPC

TCHPC allocates resources to assist research in many different fields. Below is a list of current projects been undertaken with the help of TCHPC.
  • Economics
    Compute
    C
    Micheal Smurfit Business School (UCD)
    Looking at using CUDA cards to speed up the pricing of financial options on equity and fx options using monte carlo and numerical methods.
  • Economics
    Compute
    C
    Seeking to provide a trading desk with information about what changes will occur to certain stock prices due to changes in other prices. CUDA cards will be required to carry out the computations in a time efficient manner.
  • Life Sciences
    Compute
    Dedicated human Support
    Dr. Andrew Fagan
    70-80% patients with intractable temporal lobe epilepsy (TLE) have structural abnormalities in mesial temporal lobe, ammons horn of hippocampus, entorhinal cortex in the peri hippocampal area. Furthermore, studies have shown cortical involvement outside these areas in TLE patients. The affected areas show neuronal loss, lipofuscion accumulation in neurons, glial satellosis and fibrillary gliosis. Various studies have shown presence of volume loss in mesial temporal lobe and amygdala. When there is more than 50% neuronal loss in hippocampal area (with neuropeptide Y and somatostatin reorganization), the lesion can be called as mesial temporal sclerosis. The aim of the current study was to investigate whether significant volumetric differences could be measured in the brain of TLE patients compared to age- and gender-matched controls.
  • Computer Science
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    Dr Martin Emms
    Trinity College Dublin
    Within the field of Natural Language Processing (NLP), word discrimination and sense clustering is a type of unsupervised word sense disambiguation technique that aims to distinguish automatically the sense of words by clustering their contexts. Word discrimination has many applications such as Machine Translation, Word Alignment, Information Retrieval, among others. In this particular research we will apply word discrimination methods in order to improve word alignment scores and also to track semantic change of words in time-annotated text corpora, as well as semantic variation of words across corpora written in different dialects of the same language (e.g. Irish English vs American English).
  • Life Sciences
    Compute
    Dr Isabel Rozas
    Trinity College Dublin
    Minor groove binder molecules represent potential anticancer drugs which interact with DNA to stablise the double helix and thereby reduce the rate of cellular replication. The energetics of the interactions involved are being studied by our group through the combined application of B3LYP DFT and molecular docking studies.
  • Life Sciences
    Compute
    Dr. Arun Bokde
    Trinity College Dublin
    I am completing a PhD in the Institute of Neuroscience investigating the neural substrates of emotional memory formation. I am utilizing magnetic resonance imaging (MRI) to measure functional and structural neural networks which contribute to memory formation, and how these change across the lifespan. I am using the TCHPC to analyze a type of MRI data called diffusion tensor imaging (DTI), which is a way of quantifying white matter connectivity and integrity in the human brain.
  • Life Sciences
    Compute
    Dr Gianpiero Cavalleri
    Royal College of Surgeons in Ireland
    While some epilepsies are caused by well described genetic factors, the underlying genetic component to temporal lobe epilepsy (TLE) is poorly understood. The experience of the research community to date has shown that endophenotypes are required to augment the power of genetic mapping studies in neurological disorders. Based on in-vivo quantitative magnetic resonance imaging, this programme will identify subtle structural variations in the brain which are both heritable and involved in the development of temporal lobe epilepsy (TLE). These novel endophenotypes will then be measured in a larger cohort of epilepsy patients for whom whole genome association data is already available. This combined large-scale genetics and neuroimaging dataset will be used to assist in mapping the genetic component to epilepsy.
  • Economics
    Compute
    Professor Alan Matthews
    Trinity College Dublin
    The project focuses on methodological development in areas that raise problems for modelers and analysts. This includes, in particular, the linkage between EU agricultural policy and world market; the role of new demands for food, feed and fuel on the agricultural sector, and issues that still raise methodological difficulties such as the role of transnational firms, the impact of trade liberalization on price volatility, etc. The project intends to provide applied analyses helpful to decision makers and trade negotiators.
  • Engineering
    Storage
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    Dr. Biqiong Chen
    Trinity College Dublin
    With the development of tissue engineering, the freeze!drying technology has been adopted in the fabrication of three!dimensional porous polymer scaffold and displays the advantage of easy operation, controllable of the scaffold configuration and biocleanliness.According to the mathematical simulation and experimental results, find the factors that influence the scaffold porous configuration in freeze drying processes.
  • Economics
    Compute
    Dedicated human Support
    C
    Dr Gaia Narciso
    Trinity College Dublin
    We are currently working on a project in the field of international trade, which requires to undertake data analysis using STATA. As some of the empirical specifications we use exceed the processing capacities of the available desktop computers, we were very grateful to avail of the services of TCHPC.

Last updated 19 Aug 2014Contact TCHPC: info | support.