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Trinity College Dublin

Phagocyte Viability in Tuberculosis Infection

Research Field: 
Life Sciences
Resource Type: 
Storage
Resource Class: 
C
Lead PI: 
Prof. Joseph Keane
Abstract: 
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is a major global disease burden. It most commonly infects the lungs, where it infects and replicates within macrophages and dendritic cells. These phagocytic antigen presenting cells (APCs) form part of the innate immune response, which is vital to host immunity during tuberculosis infection. My project examines the viability and function of both macrophages and dendritic cells during infection with Mtb.
Start Date: 
07/2010
Duration: 
12.00months

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